منابع مشابه
Human herpesvirus 8: an update.
The discovery of human herpesvirus 8 (HHV-8) has opened a new field in the biology and in the clinical definition of HHV-8-associated diseases. Various aspects of epidemiology, laboratory diagnosis and treatment of HHV-8 infection are still controversial. This review will summarise the most recent findings on the modalities of viral transmission in geographic areas where the virus is endemic as...
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RCA1 is one of the most intensely studied proteins in the history of cancer research, and it has more than its fair share of proposed protein partners and postulated activities. Rong Li hopes that he has made sense out of this mountain of information in a paper by Ye et al. starting on page 911. He and his coauthors suggest that BRCA1’s effects on transcription and DNA repair have as their root...
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A unified and coherent picture for the mechanism of protein folding is emerging. The crucial factor in folding is the cooperativity of multiple interactions that is required for stability of the folded state.
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Human herpesvirus 8 (HHV-8), a gammaherpesvirus implicated in Kaposi's sarcoma, primary effusion lymphoma, and Castleman's disease, encodes several pathogenically important cellular homologs. To define the HHV-8 transcription program, RNA obtained from latently infected body cavity-based lymphoma 1 cells induced to undergo lytic replication was used to query a custom HHV-8 DNA microarray contai...
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The intermediate filament protein desmin is an integral component of the cardiomyocyte and serves to maintain the overall structure and cytoskeletal organization within striated muscle cells. Desmin-related myopathy can be caused by mutations in desmin or associated proteins, which leads to intracellular accumulation of misfolded protein and production of soluble pre-amyloid oligomers, which le...
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ژورنال
عنوان ژورنال: Weekly releases (1997–2007)
سال: 2000
ISSN: 9999-1233
DOI: 10.2807/esw.04.47.01487-en